7-Oxa-3-azabicyclo[4.1.0]heptane-3-carboxylic acid, phenylMethyl ester
Benzyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate
CAS: 66207-08-7
Molecular Formula: C13H15NO3
7-Oxa-3-azabicyclo[4.1.0]heptane-3-carboxylic acid, phenylMethyl ester - Names and Identifiers
7-Oxa-3-azabicyclo[4.1.0]heptane-3-carboxylic acid, phenylMethyl ester - Physico-chemical Properties
| Molecular Formula | C13H15NO3 |
| Molar Mass | 233.26 |
| Density | 1.256±0.06 g/cm3(Predicted) |
| Boling Point | 368.4±35.0 °C(Predicted) |
| Appearance | clear liquid to slightly cloudy liquid |
| Color | Colorless to Light orange to Yellow |
| pKa | -0.88±0.20(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.54 |
7-Oxa-3-azabicyclo[4.1.0]heptane-3-carboxylic acid, phenylMethyl ester - Introduction
Benzyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate, chemical name Benzyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate, is an organic compound. Its molecular formula is C15H19NO3 and its molecular weight is 261.32. The following is a description of its nature, use, preparation and safety information:
Nature:
Benzyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate is a white or slightly yellow solid, which is solid at room temperature and soluble in some organic solvents, such as methanol, dimethyl sulfoxide and acetonitrile. Its melting point is 64-66 degrees Celsius.
Use:
Benzyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate is an important organic synthesis intermediate, which has a wide range of applications in the field of pharmaceutical synthesis, plant protection agents, dyes and spices preparation. It can be used to prepare biologically active compounds, such as anticancer drugs, antibacterial agents and antiviral drugs.
Preparation Method:
The synthesis of Benzyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate can be achieved through epoxidation and acylation reactions. First, piperidine is reacted with benzyl chloroperoxide to give N-benzyloxy-N-(3,4-epoxypiperidinyl) piperidine. The resulting product is then reacted with a chloroformate, such as methylchloroformate, to produce Benzyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate. The specific synthesis conditions need to be optimized according to the experimental requirements to ensure high yield and purity.
Safety Information:
Benzyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate is generally safe under normal use conditions, but as an organic compound, it may cause certain irritation and harm to the human body. Therefore, it is necessary to take appropriate personal protective measures, such as wearing gloves, goggles and protective clothing, when exposed to the compound. In addition, it should be kept away from fire and oxidants, and stored in a cool, dry place, away from direct sunlight. It is best to use it in a well-ventilated place to reduce the concentration of harmful gases.
Nature:
Benzyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate is a white or slightly yellow solid, which is solid at room temperature and soluble in some organic solvents, such as methanol, dimethyl sulfoxide and acetonitrile. Its melting point is 64-66 degrees Celsius.
Use:
Benzyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate is an important organic synthesis intermediate, which has a wide range of applications in the field of pharmaceutical synthesis, plant protection agents, dyes and spices preparation. It can be used to prepare biologically active compounds, such as anticancer drugs, antibacterial agents and antiviral drugs.
Preparation Method:
The synthesis of Benzyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate can be achieved through epoxidation and acylation reactions. First, piperidine is reacted with benzyl chloroperoxide to give N-benzyloxy-N-(3,4-epoxypiperidinyl) piperidine. The resulting product is then reacted with a chloroformate, such as methylchloroformate, to produce Benzyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate. The specific synthesis conditions need to be optimized according to the experimental requirements to ensure high yield and purity.
Safety Information:
Benzyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate is generally safe under normal use conditions, but as an organic compound, it may cause certain irritation and harm to the human body. Therefore, it is necessary to take appropriate personal protective measures, such as wearing gloves, goggles and protective clothing, when exposed to the compound. In addition, it should be kept away from fire and oxidants, and stored in a cool, dry place, away from direct sunlight. It is best to use it in a well-ventilated place to reduce the concentration of harmful gases.
Last Update：2024-04-09 21:32:42
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Product Name: 1-CBZ-3,4-EPOXYPIPERIDINE Visit Supplier Webpage Request for quotation
CAS: 66207-08-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 66207-08-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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